FR EA
1018-00006 · Penterra Pharmaceuticals Corp · Closing
closing-checklist.xlsx DOCUMENT IP / Technology
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Contract analysis Extract to table

[sheet: Closing Checklist]

Item No.CategoryDescription of DeliverableResponsible PartyDue DateDate CompletedStatusNotes / Comments
1Transaction AgreementsExclusive License Agreement — Execution Version, dated October 2, 2023, between Penterra Pharmaceuticals Corp. (Licensor) and Meridian Bio Therapeutics Limited (Licensee) for compound PPC-4187 (Penteracitinib); Effective Date October 20, 2023; total deal value $120,000,000Calderwood & Harkness LLP / Lam, Cheung & Firth LLP10/02/202310/02/2023CompleteSigned by Anita M. Fremont (Penterra GC) and David R. Cheung (Meridian GC). Original counterparts held by C&H.
2Transaction AgreementsSchedule A to License Agreement — Licensed Patents (7 patent families: U.S. Pat. Nos. 11,234,567 and 11,345,678; PCT/US2019/045123 national phase entries; CN Pat. No. ZL 2020 1 0456789.0; JP Pat. No. 7,012,345; KR Pat. No. 10-2345678; AU Pat. No. 2020234567; pending applications in SG, TH, MY, ID, PH, VN, TW)Calderwood & Harkness LLP10/02/202310/02/2023CompleteAttached to execution version of License Agreement.
3Transaction AgreementsSchedule B to License Agreement — Licensed Know-How (pre-clinical and clinical data packages including Study PPC-4187-201, manufacturing process for 25 mg and 50 mg tablets, analytical methods, stability data, CMC documentation from Alkerra Manufacturing Inc.)Calderwood & Harkness LLP10/02/202310/02/2023CompleteAttached to execution version of License Agreement.
4Transaction AgreementsSchedule C to License Agreement — Licensed Trademarks (PENTECLAR — U.S. Reg. No. 6,789,012; filings/registrations in HK, CN, JP, KR, AU, and additional Territory jurisdictions)Calderwood & Harkness LLP10/02/202310/02/2023CompleteAttached to execution version of License Agreement.
5Transaction AgreementsSchedule D to License Agreement — Territory (PRC incl. Hong Kong SAR and Macau SAR, Japan, Republic of Korea, Australia, New Zealand, Singapore, Thailand, Malaysia, Indonesia, Philippines, Vietnam, Taiwan)Calderwood & Harkness LLP10/02/202310/02/2023CompleteAttached to execution version of License Agreement.
6Transaction AgreementsSchedule E to License Agreement — Development Plan (Phase III development plan for Territory; milestone trigger events: $6M, $8M, $10M, $8M)Calderwood & Harkness LLP10/02/202310/02/2023CompleteAttached to execution version of License Agreement.
7Transaction AgreementsSchedule F to License Agreement — Most Favored Nation Pricing Methodology (reference price definitions, 15% floor below lowest U.S./EU5 net price, quarterly reconciliation within 45 days of quarter end, MFN adjustment payment formula)Calderwood & Harkness LLP10/02/202310/02/2023CompleteAttached to execution version of License Agreement.
8Transaction AgreementsEscrow Agreement — Execution Version, dated October 2, 2023, among Penterra, Meridian, and Velthorn National Bank, N.A. (Escrow Agent: Teresa M. D'Angelo); governs $18,000,000 upfront payment deposit and release; escrow fee $15,000 flat + $2,500/quarterCalderwood & Harkness LLP / Lam, Cheung & Firth LLP / Velthorn National Bank10/02/202310/02/2023CompleteGoverned by New York law. Originals distributed to all parties.
9Transaction AgreementsAPI Supply Agreement between Penterra and Meridian — clinical and commercial API supply at cost plus 15% markup; initial 3-year term post-closing; references Alkerra Manufacturing Inc. as CMOCalderwood & Harkness LLP10/02/202310/02/2023CompleteSigned concurrently with License Agreement.
10Transaction AgreementsTechnology Transfer Agreement between Penterra and Meridian — transfer of PPC-4187 manufacturing process know-how, analytical methods, and CMC documentation; completion deadline: 24 months from Effective Date (October 20, 2025)Calderwood & Harkness LLP10/02/202310/02/2023CompletePost-closing performance tracked separately.
11Transaction AgreementsTrademark License Agreement — Penterra to Meridian for PENTECLAR mark in Territory (exclusive license for commercialization of PPC-4187)Calderwood & Harkness LLP10/02/202310/02/2023CompleteIncludes quality control standards and usage guidelines.
12Transaction AgreementsPharmacovigilance Agreement between Penterra and Meridian — adverse event reporting, safety data exchange, PSUR obligations, global safety database responsibilities per ICH E2B/E2DCalderwood & Harkness LLP10/02/202310/02/2023CompleteSigned concurrently with License Agreement.
13Transaction AgreementsQuality Agreement (Form) — between Penterra and Meridian governing API supply specifications, quality standards, change control, deviation handling; to be executed within 60 days of Effective DateCalderwood & Harkness LLP10/02/202310/02/2023CompleteForm attached as exhibit to License Agreement. Execution deadline: December 19, 2023 (post-closing obligation).
14Closing Certificates — PenterraOfficer's Certificate — Penterra Pharmaceuticals Corp., signed by Anita M. Fremont, General Counsel, certifying representations and warranties true and correct as of closing, covenants performed, Board authorized transaction on July 18, 2023Calderwood & Harkness LLP / Penterra10/20/202310/20/2023CompleteDated October 20, 2023.
15Closing Certificates — PenterraSecretary's Certificate — Penterra Pharmaceuticals Corp. certifying board resolutions authorizing out-license of PPC-4187, incumbency of officers, certified copies of Certificate of Incorporation and Bylaws; Delaware corporation, EIN 22-3948175Calderwood & Harkness LLP / Penterra10/20/202310/20/2023CompleteDated October 20, 2023.
16Closing Certificates — PenterraGood Standing Certificate — Penterra Pharmaceuticals Corp. from Delaware Secretary of StateCalderwood & Harkness LLP / Penterra10/20/202310/12/2023CompleteCertificate obtained October 12, 2023; dated within required period of closing.
17Closing Certificates — MeridianOfficer's Certificate — Meridian Bio Therapeutics Limited, signed by David R. Cheung, General Counsel, certifying representations and warranties true and correct as of closing, covenants performedLam, Cheung & Firth LLP / Meridian10/20/202310/20/2023CompleteDated October 20, 2023.
18Closing Certificates — MeridianSecretary's/Director's Certificate — Meridian Bio Therapeutics Limited (HK Company Reg. No. 2847631) certifying board resolutions, incumbency of authorized signatories, organizational documentsLam, Cheung & Firth LLP / Meridian10/20/202310/20/2023CompleteDated October 20, 2023.
19Legal OpinionsLegal Opinion — Calderwood & Harkness LLP to Meridian Bio Therapeutics Ltd. (Marcus Delgado) re: Penterra duly organized and in good standing in Delaware; License Agreement and ancillary agreements duly authorized, executed, and delivered; valid and binding obligations; no conflicts with organizational documents or New York lawCalderwood & Harkness LLP10/20/202310/20/2023CompleteSubject to customary qualifications and assumptions.
20Legal OpinionsLegal Opinion — Lam, Cheung & Firth LLP to Penterra Pharmaceuticals Corp. (Jonathan M. Firth) re: Meridian duly organized; License Agreement and ancillary agreements duly authorized, executed, and delivered; valid and binding obligations; no conflictsLam, Cheung & Firth LLP10/20/202310/20/2023CompleteSubject to customary qualifications and assumptions.
21Escrow / FundingEscrow Funding by Meridian — $18,000,000 upfront payment deposited into escrow account at Velthorn National Bank, N.A.Meridian / Velthorn National Bank10/09/202310/06/2023CompleteFunded October 6, 2023, ahead of scheduled closing date.
22Escrow / FundingEscrow Funding Confirmation Letter — Velthorn National Bank, N.A. (Teresa M. D'Angelo) confirming receipt of $18,000,000 from MeridianVelthorn National Bank10/09/202310/06/2023CompleteLetter dated October 6, 2023; addressed to Penterra, Meridian, Calderwood & Harkness, and Lam, Cheung & Firth.
23Escrow / FundingEscrow Release of Upfront Payment ($18,000,000) to Penterra upon satisfaction of closing conditionsVelthorn National Bank / Calderwood & Harkness LLP10/20/202310/20/2023CompleteReleased on Actual Closing / Effective Date, October 20, 2023.
24Regulatory / AntitrustHSR Act / Antitrust Clearance — Confirmation that no HSR filing required (transaction is a pure IP license, does not meet HSR Act thresholds — no acquisition of voting securities or assets)Calderwood & Harkness LLP10/09/202310/05/2023CompleteConfirmed October 5, 2023. No filing required.
25Regulatory / AntitrustCFIUS Review — Confirmation not applicable (no foreign acquisition of U.S. business)Calderwood & Harkness LLP10/09/202310/05/2023CompleteNot applicable; confirmed.
26Regulatory / AntitrustChina MOFCOM/SAMR — Meridian to evaluate Technology Import/Export filing requirement under PRC Technology Import and Export Administration RegulationsLam, Cheung & Firth LLP / Meridian Shanghai10/20/202310/20/2023CompleteMeridian confirmed evaluation complete; filing to be made post-closing as required.
27IP RecordationIP Assignment / License Recordation — Filing in U.S. (USPTO)Whitford & Cascade Insurance Brokers / Calderwood & Harkness LLP10/20/202310/11/2023CompleteFiled and recorded.
28IP RecordationIP Assignment / License Recordation — Filing in China (CNIPA)Lam, Cheung & Firth LLP / Meridian Shanghai10/20/202310/15/2023CompleteFiled and recorded.
29IP RecordationIP Assignment / License Recordation — Filing in Japan (JPO)Nakamura & Takeda Law Offices10/20/202310/16/2023CompleteFiled and recorded.
30IP RecordationIP Assignment / License Recordation — Filing in South Korea (KIPO)Lam, Cheung & Firth LLP / Meridian Korea10/20/202310/17/2023CompleteFiled and recorded.
31IP RecordationIP Assignment / License Recordation — Filing in Australia (IP Australia)Lam, Cheung & Firth LLP / Meridian Australia10/20/202310/18/2023CompleteLast jurisdiction completed October 18, 2023.
32IP RecordationIP Assignment / License Recordation — Filings in remaining Territory jurisdictions (SG, TH, MY, ID, PH, VN, TW, NZ, HK, Macau)Lam, Cheung & Firth LLP / MeridianPost-ClosingPendingPost-closing obligation; to be completed on a rolling basis. Tracked in Post-Closing Obligations Tracker.
33Third-Party ConfirmationsPrescott Hale & Co. LLC — Financial advisor confirmation of deal closing and fee invoice ($1,500,000 advisory fee: $300,000 success fee [1.25% × $24M] + $1,200,000 flat fee)Prescott Hale / Penterra10/20/202310/20/2023CompleteInvoice submitted; payment to be processed by Penterra per engagement terms.
34Third-Party ConfirmationsJade Dragon Insurance Limited — Confirmation of clinical trial insurance and product liability coverage for Meridian's activities under the licenseLam, Cheung & Firth LLP / Meridian10/20/202310/19/2023CompleteCertificate of insurance received from Christine A. Lo, Underwriter.
35Post-Closing Obligations (for tracking reference)Quality Agreement — Execution by Penterra and MeridianCalderwood & Harkness LLP / Lam, Cheung & Firth LLP12/19/2023PendingDue within 60 days of Effective Date (December 19, 2023).
36Post-Closing Obligations (for tracking reference)Technology Transfer — Completion of manufacturing process transfer to Meridian's designated APAC manufacturerPenterra / Meridian10/20/2025PendingDue within 24 months of Effective Date (October 20, 2025).
37Post-Closing Obligations (for tracking reference)JSC Formation — Joint Steering Committee (3 representatives from each party); first meeting to be scheduledPenterra / MeridianPost-ClosingPendingQuarterly meetings per License Agreement.
38Post-Closing Obligations (for tracking reference)JPC Formation — Joint Patent Committee (2 representatives from each party)Penterra / MeridianPost-ClosingPendingOversees patent prosecution, maintenance, and enforcement in Territory.
39Post-Closing Obligations (for tracking reference)PRC Foreign Exchange — Outbound remittance approvals for milestone and royalty payments to be obtained by Meridian Pharma (Shanghai) Co., Ltd.Meridian ShanghaiOngoingPendingRequired for future milestone and royalty payments.
SUMMARYTotal Items: 39

Complete: 33

Pending: 6

N/A: 0

[sheet: Matter Information]

FieldValue
MatterOut-License of PPC-4187 (Penteracitinib) — Penterra Pharmaceuticals Corp. to Meridian Bio Therapeutics Ltd.
ClientPenterra Pharmaceuticals Corp. (Nasdaq: PNTR)
Client Address400 Pharma Drive, Suite 800, Princeton, NJ 08540
CounterpartyMeridian Bio Therapeutics Limited (HK Company Reg. No. 2847631)
Counterparty Address18/F, Blossom Tower, 88 Queen's Road Central, Hong Kong SAR
Counsel for LicensorCalderwood & Harkness LLP, 600 Lexington Avenue, 30th Floor, New York, NY 10022
Counsel for LicenseeLam, Cheung & Firth LLP, 25/F, Jardine House, 1 Connaught Place, Central, Hong Kong SAR
Escrow AgentVelthorn National Bank, N.A., 383 Madison Avenue, New York, NY 10179
Responsible PartnerMarcus Delgado
Billing PartnerCatherine Bloom
Lead AssociatePeter Vassiliev
Working AssociateWendy Schultz
Tax SpecialistSylvia Hartwell
Signing DateOctober 2, 2023
Scheduled Closing DateOctober 9, 2023
Actual Closing / Effective DateOctober 20, 2023
Total Deal Value$120,000,000 ($18M upfront + $32M development milestones + $25M regulatory milestones + $45M commercial milestones)
Upfront Payment$18,000,000 (via escrow)
Governing LawState of New York
Dispute ResolutionICC International Court of Arbitration, New York, NY; panel of 3 arbitrators
Last UpdatedOctober 20, 2023
Prepared ByPeter Vassiliev and Wendy Schultz, Calderwood & Harkness LLP