1018-00006
· Penterra Pharmaceuticals Corp · Closing
closing-checklist.xlsx
DOCUMENT
IP / Technology
[sheet: Closing Checklist]
| Item No. | Category | Description of Deliverable | Responsible Party | Due Date | Date Completed | Status | Notes / Comments |
| 1 | Transaction Agreements | Exclusive License Agreement — Execution Version, dated October 2, 2023, between Penterra Pharmaceuticals Corp. (Licensor) and Meridian Bio Therapeutics Limited (Licensee) for compound PPC-4187 (Penteracitinib); Effective Date October 20, 2023; total deal value $120,000,000 | Calderwood & Harkness LLP / Lam, Cheung & Firth LLP | 10/02/2023 | 10/02/2023 | Complete | Signed by Anita M. Fremont (Penterra GC) and David R. Cheung (Meridian GC). Original counterparts held by C&H. |
| 2 | Transaction Agreements | Schedule A to License Agreement — Licensed Patents (7 patent families: U.S. Pat. Nos. 11,234,567 and 11,345,678; PCT/US2019/045123 national phase entries; CN Pat. No. ZL 2020 1 0456789.0; JP Pat. No. 7,012,345; KR Pat. No. 10-2345678; AU Pat. No. 2020234567; pending applications in SG, TH, MY, ID, PH, VN, TW) | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Attached to execution version of License Agreement. |
| 3 | Transaction Agreements | Schedule B to License Agreement — Licensed Know-How (pre-clinical and clinical data packages including Study PPC-4187-201, manufacturing process for 25 mg and 50 mg tablets, analytical methods, stability data, CMC documentation from Alkerra Manufacturing Inc.) | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Attached to execution version of License Agreement. |
| 4 | Transaction Agreements | Schedule C to License Agreement — Licensed Trademarks (PENTECLAR — U.S. Reg. No. 6,789,012; filings/registrations in HK, CN, JP, KR, AU, and additional Territory jurisdictions) | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Attached to execution version of License Agreement. |
| 5 | Transaction Agreements | Schedule D to License Agreement — Territory (PRC incl. Hong Kong SAR and Macau SAR, Japan, Republic of Korea, Australia, New Zealand, Singapore, Thailand, Malaysia, Indonesia, Philippines, Vietnam, Taiwan) | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Attached to execution version of License Agreement. |
| 6 | Transaction Agreements | Schedule E to License Agreement — Development Plan (Phase III development plan for Territory; milestone trigger events: $6M, $8M, $10M, $8M) | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Attached to execution version of License Agreement. |
| 7 | Transaction Agreements | Schedule F to License Agreement — Most Favored Nation Pricing Methodology (reference price definitions, 15% floor below lowest U.S./EU5 net price, quarterly reconciliation within 45 days of quarter end, MFN adjustment payment formula) | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Attached to execution version of License Agreement. |
| 8 | Transaction Agreements | Escrow Agreement — Execution Version, dated October 2, 2023, among Penterra, Meridian, and Velthorn National Bank, N.A. (Escrow Agent: Teresa M. D'Angelo); governs $18,000,000 upfront payment deposit and release; escrow fee $15,000 flat + $2,500/quarter | Calderwood & Harkness LLP / Lam, Cheung & Firth LLP / Velthorn National Bank | 10/02/2023 | 10/02/2023 | Complete | Governed by New York law. Originals distributed to all parties. |
| 9 | Transaction Agreements | API Supply Agreement between Penterra and Meridian — clinical and commercial API supply at cost plus 15% markup; initial 3-year term post-closing; references Alkerra Manufacturing Inc. as CMO | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Signed concurrently with License Agreement. |
| 10 | Transaction Agreements | Technology Transfer Agreement between Penterra and Meridian — transfer of PPC-4187 manufacturing process know-how, analytical methods, and CMC documentation; completion deadline: 24 months from Effective Date (October 20, 2025) | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Post-closing performance tracked separately. |
| 11 | Transaction Agreements | Trademark License Agreement — Penterra to Meridian for PENTECLAR mark in Territory (exclusive license for commercialization of PPC-4187) | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Includes quality control standards and usage guidelines. |
| 12 | Transaction Agreements | Pharmacovigilance Agreement between Penterra and Meridian — adverse event reporting, safety data exchange, PSUR obligations, global safety database responsibilities per ICH E2B/E2D | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Signed concurrently with License Agreement. |
| 13 | Transaction Agreements | Quality Agreement (Form) — between Penterra and Meridian governing API supply specifications, quality standards, change control, deviation handling; to be executed within 60 days of Effective Date | Calderwood & Harkness LLP | 10/02/2023 | 10/02/2023 | Complete | Form attached as exhibit to License Agreement. Execution deadline: December 19, 2023 (post-closing obligation). |
| 14 | Closing Certificates — Penterra | Officer's Certificate — Penterra Pharmaceuticals Corp., signed by Anita M. Fremont, General Counsel, certifying representations and warranties true and correct as of closing, covenants performed, Board authorized transaction on July 18, 2023 | Calderwood & Harkness LLP / Penterra | 10/20/2023 | 10/20/2023 | Complete | Dated October 20, 2023. |
| 15 | Closing Certificates — Penterra | Secretary's Certificate — Penterra Pharmaceuticals Corp. certifying board resolutions authorizing out-license of PPC-4187, incumbency of officers, certified copies of Certificate of Incorporation and Bylaws; Delaware corporation, EIN 22-3948175 | Calderwood & Harkness LLP / Penterra | 10/20/2023 | 10/20/2023 | Complete | Dated October 20, 2023. |
| 16 | Closing Certificates — Penterra | Good Standing Certificate — Penterra Pharmaceuticals Corp. from Delaware Secretary of State | Calderwood & Harkness LLP / Penterra | 10/20/2023 | 10/12/2023 | Complete | Certificate obtained October 12, 2023; dated within required period of closing. |
| 17 | Closing Certificates — Meridian | Officer's Certificate — Meridian Bio Therapeutics Limited, signed by David R. Cheung, General Counsel, certifying representations and warranties true and correct as of closing, covenants performed | Lam, Cheung & Firth LLP / Meridian | 10/20/2023 | 10/20/2023 | Complete | Dated October 20, 2023. |
| 18 | Closing Certificates — Meridian | Secretary's/Director's Certificate — Meridian Bio Therapeutics Limited (HK Company Reg. No. 2847631) certifying board resolutions, incumbency of authorized signatories, organizational documents | Lam, Cheung & Firth LLP / Meridian | 10/20/2023 | 10/20/2023 | Complete | Dated October 20, 2023. |
| 19 | Legal Opinions | Legal Opinion — Calderwood & Harkness LLP to Meridian Bio Therapeutics Ltd. (Marcus Delgado) re: Penterra duly organized and in good standing in Delaware; License Agreement and ancillary agreements duly authorized, executed, and delivered; valid and binding obligations; no conflicts with organizational documents or New York law | Calderwood & Harkness LLP | 10/20/2023 | 10/20/2023 | Complete | Subject to customary qualifications and assumptions. |
| 20 | Legal Opinions | Legal Opinion — Lam, Cheung & Firth LLP to Penterra Pharmaceuticals Corp. (Jonathan M. Firth) re: Meridian duly organized; License Agreement and ancillary agreements duly authorized, executed, and delivered; valid and binding obligations; no conflicts | Lam, Cheung & Firth LLP | 10/20/2023 | 10/20/2023 | Complete | Subject to customary qualifications and assumptions. |
| 21 | Escrow / Funding | Escrow Funding by Meridian — $18,000,000 upfront payment deposited into escrow account at Velthorn National Bank, N.A. | Meridian / Velthorn National Bank | 10/09/2023 | 10/06/2023 | Complete | Funded October 6, 2023, ahead of scheduled closing date. |
| 22 | Escrow / Funding | Escrow Funding Confirmation Letter — Velthorn National Bank, N.A. (Teresa M. D'Angelo) confirming receipt of $18,000,000 from Meridian | Velthorn National Bank | 10/09/2023 | 10/06/2023 | Complete | Letter dated October 6, 2023; addressed to Penterra, Meridian, Calderwood & Harkness, and Lam, Cheung & Firth. |
| 23 | Escrow / Funding | Escrow Release of Upfront Payment ($18,000,000) to Penterra upon satisfaction of closing conditions | Velthorn National Bank / Calderwood & Harkness LLP | 10/20/2023 | 10/20/2023 | Complete | Released on Actual Closing / Effective Date, October 20, 2023. |
| 24 | Regulatory / Antitrust | HSR Act / Antitrust Clearance — Confirmation that no HSR filing required (transaction is a pure IP license, does not meet HSR Act thresholds — no acquisition of voting securities or assets) | Calderwood & Harkness LLP | 10/09/2023 | 10/05/2023 | Complete | Confirmed October 5, 2023. No filing required. |
| 25 | Regulatory / Antitrust | CFIUS Review — Confirmation not applicable (no foreign acquisition of U.S. business) | Calderwood & Harkness LLP | 10/09/2023 | 10/05/2023 | Complete | Not applicable; confirmed. |
| 26 | Regulatory / Antitrust | China MOFCOM/SAMR — Meridian to evaluate Technology Import/Export filing requirement under PRC Technology Import and Export Administration Regulations | Lam, Cheung & Firth LLP / Meridian Shanghai | 10/20/2023 | 10/20/2023 | Complete | Meridian confirmed evaluation complete; filing to be made post-closing as required. |
| 27 | IP Recordation | IP Assignment / License Recordation — Filing in U.S. (USPTO) | Whitford & Cascade Insurance Brokers / Calderwood & Harkness LLP | 10/20/2023 | 10/11/2023 | Complete | Filed and recorded. |
| 28 | IP Recordation | IP Assignment / License Recordation — Filing in China (CNIPA) | Lam, Cheung & Firth LLP / Meridian Shanghai | 10/20/2023 | 10/15/2023 | Complete | Filed and recorded. |
| 29 | IP Recordation | IP Assignment / License Recordation — Filing in Japan (JPO) | Nakamura & Takeda Law Offices | 10/20/2023 | 10/16/2023 | Complete | Filed and recorded. |
| 30 | IP Recordation | IP Assignment / License Recordation — Filing in South Korea (KIPO) | Lam, Cheung & Firth LLP / Meridian Korea | 10/20/2023 | 10/17/2023 | Complete | Filed and recorded. |
| 31 | IP Recordation | IP Assignment / License Recordation — Filing in Australia (IP Australia) | Lam, Cheung & Firth LLP / Meridian Australia | 10/20/2023 | 10/18/2023 | Complete | Last jurisdiction completed October 18, 2023. |
| 32 | IP Recordation | IP Assignment / License Recordation — Filings in remaining Territory jurisdictions (SG, TH, MY, ID, PH, VN, TW, NZ, HK, Macau) | Lam, Cheung & Firth LLP / Meridian | Post-Closing | Pending | Post-closing obligation; to be completed on a rolling basis. Tracked in Post-Closing Obligations Tracker. | |
| 33 | Third-Party Confirmations | Prescott Hale & Co. LLC — Financial advisor confirmation of deal closing and fee invoice ($1,500,000 advisory fee: $300,000 success fee [1.25% × $24M] + $1,200,000 flat fee) | Prescott Hale / Penterra | 10/20/2023 | 10/20/2023 | Complete | Invoice submitted; payment to be processed by Penterra per engagement terms. |
| 34 | Third-Party Confirmations | Jade Dragon Insurance Limited — Confirmation of clinical trial insurance and product liability coverage for Meridian's activities under the license | Lam, Cheung & Firth LLP / Meridian | 10/20/2023 | 10/19/2023 | Complete | Certificate of insurance received from Christine A. Lo, Underwriter. |
| 35 | Post-Closing Obligations (for tracking reference) | Quality Agreement — Execution by Penterra and Meridian | Calderwood & Harkness LLP / Lam, Cheung & Firth LLP | 12/19/2023 | Pending | Due within 60 days of Effective Date (December 19, 2023). | |
| 36 | Post-Closing Obligations (for tracking reference) | Technology Transfer — Completion of manufacturing process transfer to Meridian's designated APAC manufacturer | Penterra / Meridian | 10/20/2025 | Pending | Due within 24 months of Effective Date (October 20, 2025). | |
| 37 | Post-Closing Obligations (for tracking reference) | JSC Formation — Joint Steering Committee (3 representatives from each party); first meeting to be scheduled | Penterra / Meridian | Post-Closing | Pending | Quarterly meetings per License Agreement. | |
| 38 | Post-Closing Obligations (for tracking reference) | JPC Formation — Joint Patent Committee (2 representatives from each party) | Penterra / Meridian | Post-Closing | Pending | Oversees patent prosecution, maintenance, and enforcement in Territory. | |
| 39 | Post-Closing Obligations (for tracking reference) | PRC Foreign Exchange — Outbound remittance approvals for milestone and royalty payments to be obtained by Meridian Pharma (Shanghai) Co., Ltd. | Meridian Shanghai | Ongoing | Pending | Required for future milestone and royalty payments. | |
| SUMMARY | Total Items: 39 |
Complete: 33
Pending: 6
N/A: 0
[sheet: Matter Information]
| Field | Value |
| Matter | Out-License of PPC-4187 (Penteracitinib) — Penterra Pharmaceuticals Corp. to Meridian Bio Therapeutics Ltd. |
| Client | Penterra Pharmaceuticals Corp. (Nasdaq: PNTR) |
| Client Address | 400 Pharma Drive, Suite 800, Princeton, NJ 08540 |
| Counterparty | Meridian Bio Therapeutics Limited (HK Company Reg. No. 2847631) |
| Counterparty Address | 18/F, Blossom Tower, 88 Queen's Road Central, Hong Kong SAR |
| Counsel for Licensor | Calderwood & Harkness LLP, 600 Lexington Avenue, 30th Floor, New York, NY 10022 |
| Counsel for Licensee | Lam, Cheung & Firth LLP, 25/F, Jardine House, 1 Connaught Place, Central, Hong Kong SAR |
| Escrow Agent | Velthorn National Bank, N.A., 383 Madison Avenue, New York, NY 10179 |
| Responsible Partner | Marcus Delgado |
| Billing Partner | Catherine Bloom |
| Lead Associate | Peter Vassiliev |
| Working Associate | Wendy Schultz |
| Tax Specialist | Sylvia Hartwell |
| Signing Date | October 2, 2023 |
| Scheduled Closing Date | October 9, 2023 |
| Actual Closing / Effective Date | October 20, 2023 |
| Total Deal Value | $120,000,000 ($18M upfront + $32M development milestones + $25M regulatory milestones + $45M commercial milestones) |
| Upfront Payment | $18,000,000 (via escrow) |
| Governing Law | State of New York |
| Dispute Resolution | ICC International Court of Arbitration, New York, NY; panel of 3 arbitrators |
| Last Updated | October 20, 2023 |
| Prepared By | Peter Vassiliev and Wendy Schultz, Calderwood & Harkness LLP |