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PRIVILEGED AND CONFIDENTIAL ATTORNEY-CLIENT COMMUNICATION ATTORNEY WORK PRODUCT

This memorandum is a privileged and confidential attorney-client communication and constitutes attorney work product prepared in anticipation of litigation and for the purpose of providing legal advice to Penterra Pharmaceuticals Corp. It is protected from disclosure by the attorney-client privilege, the work product doctrine, and all other applicable protections. This memorandum and its contents may not be disclosed, distributed, or reproduced, in whole or in part, without the prior written authorization of Calderwood & Harkness LLP.

CALDERWOOD & HARKNESS LLP 1735 Market Street, Suite 3100 Philadelphia, PA 19103

MEMORANDUM

December 18, 2023

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I. Executive Summary

This memorandum analyzes whether Penterra Pharmaceuticals Corp. ("PPC") should pursue competent authority relief under the Convention Between the Government of the United States of America and the Government of Ireland for the Avoidance of Double Taxation and the Prevention of Fiscal Evasion with Respect to Taxes on Income and Capital Gains, signed November 28, 1997, as amended by Protocol signed July 24, 1999 (the "U.S.-Ireland Treaty" or the "Treaty"), to mitigate or eliminate the double taxation that would arise from the Internal Revenue Service's ("IRS") proposed transfer pricing adjustments under Internal Revenue Code ("IRC") § 482 for tax years 2017 through 2020, totaling $380.4 million.

On October 12, 2023, the IRS issued a Notice of Proposed Adjustment ("NOPA") proposing substantial adjustments to intercompany transactions between PPC (EIN 22-3741856) and its Irish subsidiary, Penterra Biopharma International DAC ("PBI," Irish Tax Reference No. 3218764T). The proposed adjustments target both PBI's cost-sharing payments under a 2012 cost-sharing arrangement and the royalty rate charged under a legacy intellectual property license agreement. PPC filed its formal Protest on December 22, 2023, and the matter is now transitioning to IRS Appeals for consideration. An Appeals conference has been scheduled for February 28, 2024.

The central question addressed in this memorandum is whether, and when, PPC should initiate a Mutual Agreement Procedure ("MAP") request under Article 25 of the Treaty. A MAP request would invoke the bilateral competent authority process, pursuant to which the U.S. Competent Authority (the IRS, acting through the Advance Pricing and Mutual Agreement Program, or "APMA") and the Irish Competent Authority (the Irish Revenue Commissioners) would endeavor to resolve the double taxation that results when one jurisdiction increases the taxable income of an enterprise without a corresponding decrease by the other jurisdiction.

Our key conclusion is as follows: While a MAP request is a viable and well-founded mechanism for seeking relief from double taxation, and PPC possesses a clear treaty right to invoke the MAP under Article 25(1), we recommend that PPC defer the substantive MAP filing until the outcome of the IRS Appeals process is known. This recommendation rests on considerations of timing, strategic leverage in the Appeals negotiation, and cost efficiency. However, to preserve PPC's procedural rights, we recommend that PPC take certain protective steps now — specifically, filing a brief protective MAP request with APMA and instructing Irish counsel at Thornbury & Keogh ("T&K") to provide informal notification to the Irish Revenue Commissioners.

This recommendation is informed by our assessment of the likely Appeals outcome. As discussed in our separate memorandum of December 12, 2023, regarding Appeals strategy, we believe there is a reasonable basis to achieve settlement at approximately 10–15% of the proposed $380.4 million adjustment — that is, in the range of approximately $38 million to $57 million. At the midpoint of our target range (approximately $47.6 million), the double-tax exposure on the settled amount would be correspondingly reduced, potentially to a level where a full bilateral MAP proceeding is economically unjustified relative to its cost, particularly if PBI can obtain a unilateral corresponding adjustment directly from the Irish Revenue Commissioners without invoking the formal MAP process.

The balance of this memorandum sets forth the factual background, the relevant legal framework, our analysis of the arguments for and against pursuing a MAP request at this time, the procedural requirements for filing, the potential outcomes, and our specific recommendations regarding next steps.

II. Factual Background

A. PPC's Corporate Structure and Intercompany Arrangements

1. Penterra Pharmaceuticals Corp. (PPC)

PPC is a Delaware corporation, publicly traded on the Nasdaq Stock Market under the ticker symbol "PPCA," with its principal executive offices located at 2200 Independence Boulevard, Princeton Junction, New Jersey 08550. PPC is a specialty pharmaceutical and biotechnology company focused on three primary therapeutic areas: oncology, immunology, and rare disease. For the fiscal year ended December 31, 2020, PPC reported consolidated revenue of approximately $6.82 billion and pre-tax income of approximately $1.47 billion. PPC files its U.S. federal income tax returns on a calendar-year basis and is the common parent of an affiliated group filing consolidated returns.

PPC's U.S. operations encompass the full spectrum of pharmaceutical value-chain activities, including research and development, regulatory affairs, clinical trial management, manufacturing, sales, and marketing for the Americas region. PPC maintains substantial research facilities in Princeton Junction, New Jersey, and Cambridge, Massachusetts, and employs approximately 8,400 persons in the United States.

2. Ownership Chain and Intermediate Holding Entity

PPC's Irish operations are conducted through a two-tier structure. PPC directly owns 100% of the share capital of Penterra Holdings Luxembourg S.à r.l. ("PHL"), a société à responsabilité limitée organized under the laws of the Grand Duchy of Luxembourg, with its registered office at 14, rue Aldringen, L-1118 Luxembourg (Luxembourg Registre de Commerce et des Sociétés No. B 168452). PHL is treated as a disregarded entity for U.S. federal income tax purposes pursuant to the check-the-box regulations under Treasury Regulation § 301.7701-3. PHL's sole material asset is its 100% ownership of the ordinary shares of PBI. PHL was interposed in the structure for European holding and financing purposes, and its treatment as a disregarded entity for U.S. tax purposes means that, for purposes of the IRC § 482 analysis and the Treaty MAP analysis, the relevant bilateral relationship is between PPC (U.S.) and PBI (Ireland).

3. Penterra Biopharma International DAC (PBI)

PBI is a designated activity company organized under the laws of Ireland, incorporated on March 15, 2012, with its registered office at 4th Floor, Claremont House, Sandyford Business Park, Dublin D18 K7T4, Ireland. PBI's Managing Director is Aidan Naughton. PBI functions as the intellectual property holding company and commercial principal for PPC's operations outside the Americas (i.e., Europe, Middle East, Africa, and Asia-Pacific). PBI holds the rights to exploit certain PPC-developed pharmaceutical compounds and technologies outside the Americas, both through a legacy intellectual property license (for pre-2012 compounds) and through its participation in a cost-sharing arrangement (for post-2012 developed intangibles).

As of December 31, 2020, PBI employed 185 persons — a significant increase from the 52 employees at the time of its incorporation in 2012. This growth reflects PBI's expanded operational role in commercial decision-making, regulatory strategy for non-Americas markets, medical affairs, pricing and market access, and supply chain management. PBI's employees include experienced pharmaceutical executives in the areas of commercial operations, regulatory affairs, medical affairs, finance, legal, and business development.

For the fiscal year ended December 31, 2020, PBI reported revenue of approximately €2.14 billion and pre-tax income of approximately €1.06 billion. PBI claims the benefit of Ireland's Knowledge Development box ("KDB") at an effective tax rate of 6.25% on qualifying intellectual property income, pursuant to Section 769R of the Taxes Consolidation Act 1997 (as amended). Income not qualifying for the KDB is subject to the standard Irish corporation tax rate for trading income of 12.5%.

4. Penterra Manufacturing Ireland Ltd. (PMI)

Penterra Manufacturing Ireland Ltd. ("PMI") is an Irish private limited company (Companies Registration Office No. 512347), with its principal place of business at Unit 7, Ringaskiddy Industrial Estate, Co. Cork, Ireland. PMI operates as a contract manufacturer for PBI under a contract manufacturing agreement, pursuant to which PMI manufactures finished pharmaceutical products for the non-Americas territory on a cost-plus basis, receiving a markup of 8% on its fully loaded manufacturing costs. PMI employs approximately 620 persons at its Ringaskiddy facility. PMI's transfer pricing is not at issue in the current IRS examination.

5. Cost-Sharing Arrangement (CSA)

Effective July 1, 2012, PPC and PBI entered into a Qualified Cost Sharing Arrangement (the "CSA") within the meaning of Treasury Regulation § 1.482-7. Under the CSA, PBI co-funds a share of PPC's ongoing research and development costs in exchange for the right to exploit the resulting intangible property outside the Americas. PPC retains the right to exploit the resulting intangible property within the Americas. The cost-sharing percentages are determined annually based on each party's reasonably anticipated benefits from the exploitation of the cost-shared intangibles, measured by reference to projected revenues in each party's territory.

In connection with the establishment of the CSA, PBI made a Platform Contribution Transaction ("PCT") payment to PPC of $312 million as a lump sum on July 1, 2012. The PCT payment compensated PPC for making available to the CSA pre-existing intangible property and other platform contributions, including the value of PPC's existing research pipeline, development capabilities, and other resources that would contribute to future cost-shared intangible development.

PBI's cost-sharing percentages and payments for the tax years at issue were as follows:

The cost-sharing percentages increased over the period as PBI's non-Americas revenues grew relative to PPC's Americas revenues, reflecting the increasing market penetration of PPC's key products in European and Asia-Pacific markets.

6. Legacy IP License

Separate from the CSA, PBI licenses from PPC the rights to exploit certain pre-2012 pharmaceutical compounds and intellectual property in the non-Americas territory under a Legacy IP License Agreement effective July 1, 2012 (the "Legacy License"). The Legacy License provides for a running royalty of 4.5% of PBI's net sales attributable to the licensed pre-2012 compounds. The key pre-2012 compounds include certain legacy oncology compounds and a mature immunology product whose patents began expiring during the period at issue.

Legacy net sales and royalty payments for the tax years at issue were as follows:

The declining legacy net sales reflect the natural lifecycle of pre-2012 compounds, including generic competition and patent expirations in certain non-Americas jurisdictions.

7. Key Products

PPC's three key products during the 2017–2020 period, and their respective revenue profiles, are as follows:

• Veritaxol (oncology — PD-L1 inhibitor): 2020 global net revenue of $3.12 billion, of which $1.34 billion was attributable to the non-Americas territory (PBI). Veritaxol received its initial FDA approval in 2015 and EMA approval in 2016. It is the largest single product in PPC's portfolio and the primary driver of PBI's revenue growth.

• Imvara (immunology — IL-23 monoclonal antibody): 2020 global net revenue of $1.87 billion, of which $0.79 billion was attributable to the non-Americas territory (PBI). Imvara received FDA approval in 2017 and EMA approval in 2018.

• Cerulon (rare disease — enzyme replacement therapy): 2020 global net revenue of $0.62 billion, of which $0.28 billion was attributable to the non-Americas territory (PBI). Cerulon received orphan drug designations in both the U.S. and EU.

Veritaxol and Imvara are both cost-shared intangibles developed under the CSA. Cerulon's development was substantially completed prior to the establishment of the CSA, and PBI's commercialization of Cerulon outside the Americas is governed by the Legacy License.

B. The IRS Proposed Adjustments

1. Examination History

The IRS opened an examination of PPC's consolidated federal income tax returns for tax years 2017 through 2020 on May 16, 2022, when PPC received Letter 2205-A (Notification of Examination) from the IRS Large Business and International Division ("LB&I"). The examination was assigned to the Northeast Transfer Pricing Practice, under Exam Team Identification Number LB&I-NE-TP-2022-00641. The examination team was composed of the following key personnel:

• Lead Revenue Agent: Patricia Dunleavy

• Supervisory Revenue Agent: Gerald Meskill

• IRS Economist: Dr. Alan Washburne

• Chief Counsel Attorney-Advisor: Franklin Rosario

• Senior Counsel: Donna Hirabayashi

The examination focused primarily on PPC's intercompany transfer pricing with PBI, including the CSA cost-sharing percentages and the Legacy License royalty rate. Over the course of the examination, the IRS issued a total of 47 Information Document Requests ("IDRs") between June 2022 and September 2023, covering topics including PBI's functional analysis, comparable company data, PPC's contemporaneous transfer pricing documentation, the CSA agreement and related analyses, and the Legacy License terms and economic support.

2. Notice of Proposed Adjustment (NOPA)

On October 12, 2023, the IRS issued a Notice of Proposed Adjustment ("NOPA") proposing the following adjustments to PPC's taxable income for tax years 2017 through 2020:

a. CSA Cost-Sharing Ratio Adjustment

The IRS proposes to increase PBI's cost-sharing percentages by approximately 8 to 12 percentage points for each year at issue, on the basis that PPC's contemporaneous reasonably anticipated benefit ("RAB") analysis understated PBI's expected benefits from the cost-shared intangibles. The IRS Economist, Dr. Washburne, contends that the RAB calculation should incorporate certain market-access and regulatory benefits specific to PBI's non-Americas territory that PPC's analysis did not adequately capture. The resulting proposed income adjustments to PPC (i.e., additional income allocated to PPC reflecting PBI's understated cost-sharing payments) are as follows:

b. Royalty Rate Adjustment

The IRS proposes to increase the Legacy License royalty rate from 4.5% to 11.0% of PBI's non-Americas net sales of licensed pre-2012 compounds, on the basis that the 4.5% rate does not reflect arm's-length compensation for the intangible property licensed by PPC to PBI. The IRS's comparability analysis, prepared by Dr. Washburne, relies on a set of purportedly comparable license agreements that the IRS contends support a royalty rate in the range of 9.5% to 12.5%, with a median of 11.0%. The resulting proposed income adjustments are as follows:

c. Correlative Offset

The IRS examination team allowed a partial correlative offset of $42.65 million, reflecting certain adjustments that would reduce PPC's income in other categories as a consequence of the proposed § 482 reallocations. This offset was calculated by the examination team and is reflected in the NOPA.

d. Net Proposed Adjustment and Penalty

The net proposed income adjustment, after the correlative offset, is as follows:

In addition, the IRS proposed a substantial valuation misstatement penalty under IRC § 6662(e) of 20% of the underpayment of tax attributable to the net § 482 allocation, which the IRS calculated at $15.98 million.

3. Procedural Status

The IRS issued a 30-Day Letter on November 8, 2023, affording PPC the opportunity to file a formal Protest and request a conference with IRS Appeals. PPC filed its formal Protest on December 22, 2023, as discussed in our separate memorandum of the same date. The case is expected to be assigned to an IRS Appeals Officer in January 2024, and an Appeals conference has been scheduled for February 28, 2024.

C. The Double Taxation Risk

The central concern motivating this memorandum is the risk of economic double taxation. If the IRS's proposed $380.4 million adjustment — or any portion thereof, whether through full sustention or through settlement at Appeals — is finalized and increases PPC's U.S. taxable income, PBI's income as reported to the Irish Revenue Commissioners for the corresponding tax years will not be automatically or correspondingly reduced. PBI has already filed its Irish corporation tax returns for the years at issue and has already paid Irish corporation tax on the income that the IRS now seeks to reallocate to PPC. In the absence of affirmative action by the Irish Revenue Commissioners to grant a correlative downward adjustment to PBI's Irish taxable income, the same income will be taxed twice: once by the United States (at the applicable U.S. corporate tax rate of 35% for 2017 and 21% for 2018–2020) and once by Ireland (at 6.25% for KDB-qualifying income or 12.5% for other trading income).

To illustrate the magnitude of this exposure:

• At the full proposed adjustment of $380.4 million: The incremental U.S. federal income tax on the adjustment would be approximately $79.88 million (applying a blended rate reflecting the 35% rate for 2017 and the 21% rate for 2018–2020). The Irish tax already paid by PBI on the corresponding income is estimated at approximately $23.8 million to $47.6 million (depending on the allocation between KDB-qualifying and non-qualifying income). The aggregate tax burden on the disputed income would thus significantly exceed the tax that either jurisdiction, standing alone, would have imposed.

• At our target settlement level of 10–15% of $380.4 million (i.e., approximately $38 million to $57 million): The double-tax exposure is correspondingly reduced but still present. At a midpoint settlement of $47.6 million, the incremental U.S. tax would be approximately $10.0 million, and the Irish tax already paid on the corresponding income would be approximately $3.0 million to $6.0 million. While smaller, this represents a real and quantifiable cost that should be addressed if it can be done efficiently.

The mechanism for eliminating this double taxation — whether through the bilateral MAP process under Article 25 of the Treaty, through a unilateral corresponding adjustment by the Irish Revenue Commissioners under Article 9(2), or through the foreign tax credit provisions of the IRC — is the subject of the analysis that follows.

III. Legal Framework for Competent Authority / MAP Relief

A. U.S.-Ireland Income Tax Treaty — Article 25 (Mutual Agreement Procedure)

The primary treaty mechanism for addressing the double taxation at issue is the Mutual Agreement Procedure set forth in Article 25 of the U.S.-Ireland Treaty. The relevant provisions are as follows:

Article 25(1) provides that where a person considers that the actions of one or both of the Contracting States result or will result in taxation not in accordance with the provisions of the Treaty, that person may, irrespective of the remedies provided by the domestic law of those States, present the case to the competent authority of the Contracting State of which it is a resident (or, in certain cases, of which it is a national). The case must be presented within three years from the first notification of the action resulting in taxation not in accordance with the provisions of the Treaty.

This provision establishes the taxpayer's standing to initiate the MAP process. PPC, as a resident of the United States, has the right to present its case to the U.S. Competent Authority. The three-year filing deadline runs from the "first notification" of the offending action — in this case, the NOPA issued on October 12, 2023. Accordingly, PPC must file its MAP request no later than October 12, 2026. While this deadline is not immediately pressing, we recommend a protective filing well in advance to eliminate any risk of inadvertent forfeiture.

Article 25(2) provides that the competent authority shall endeavor, if the objection appears to it to be justified and if it is not itself able to arrive at a satisfactory solution, to resolve the case by mutual agreement with the competent authority of the other Contracting State, with a view to the avoidance of taxation which is not in accordance with the provisions of the Treaty. Any agreement reached shall be implemented notwithstanding any time limits in the domestic law of the Contracting States.

This provision imposes an obligation on the competent authorities to "endeavor" to resolve the case — an obligation of effort, not of result. The competent authorities are not required to reach agreement, and the Treaty does not contain a mandatory binding arbitration provision (unlike certain other U.S. tax treaties, such as the U.S.-Germany and U.S.-Canada treaties). This is a significant limitation, discussed further in Section VI.C below.

Article 25(3) provides that the competent authorities of the Contracting States shall endeavor to resolve by mutual agreement any difficulties or doubts arising as to the interpretation or application of the Treaty. They may also consult together for the elimination of double taxation in cases not provided for in the Treaty.

This provision broadens the scope of the MAP process beyond specific taxpayer cases to encompass general interpretive and application questions, and extends the competent authorities' mandate to address double taxation even in situations not explicitly covered by other Treaty articles.

Identification of Competent Authorities: The U.S. Competent Authority is the IRS, which exercises its competent authority functions through the Advance Pricing and Mutual Agreement Program ("APMA"), a unit within LB&I. The Irish Competent Authority is the Irish Revenue Commissioners, acting through the Competent Authority Division within the Large Cases Division.

B. Article 9 (Associated Enterprises) — The Treaty Basis for Transfer Pricing Adjustments

Article 9 of the Treaty provides the substantive basis for transfer pricing adjustments and correlative relief:

Article 9(1) permits a Contracting State to adjust the profits of an enterprise where conditions between associated enterprises differ from those that would be made between independent enterprises dealing at arm's length. This provision authorizes the IRS's proposed § 482 adjustment, to the extent it is consistent with the arm's-length principle as reflected in the Treaty.

Article 9(2) is the critical provision for correlative relief. It provides that where one Contracting State includes in the profits of an enterprise of that State — and taxes accordingly — profits on which an enterprise of the other Contracting State has been charged to tax in that other State, and the profits so included are profits which would have accrued to the first-mentioned enterprise if the conditions made between the two enterprises had been those which would have been made between independent enterprises, then the other State shall make an appropriate adjustment to the amount of the tax charged therein on those profits. In determining such adjustment, due regard shall be had to the other provisions of the Treaty, and the competent authorities of the Contracting States shall if necessary consult each other.

Article 9(2) is the primary mechanism by which Ireland would reduce PBI's Irish taxable income to correspond to any U.S. § 482 adjustment sustained against PPC. It is important to note that Article 9(2) does not impose an automatic or mandatory obligation on Ireland to provide a correlative adjustment. The provision requires that Ireland "shall make an appropriate adjustment" — but only if Ireland "considers" that the primary adjustment by the United States is justified under the arm's-length principle. In practice, this means that the Irish Revenue Commissioners retain the right to independently evaluate the merits of the U.S. adjustment before granting correlative relief. The MAP process under Article 25 is the procedural vehicle through which the two competent authorities discuss and resolve any disagreement regarding whether a correlative adjustment is warranted.

C. Rev. Proc. 2015-40 — U.S. Competent Authority Procedures

Revenue Procedure 2015-40, 2015-35 I.R.B. 236, sets forth the administrative procedures governing requests for competent authority assistance under U.S. income tax treaties, including MAP requests relating to transfer pricing adjustments under IRC § 482.

Filing Requirements. A taxpayer seeking U.S. competent authority assistance must submit a written request to the U.S. Competent Authority (APMA) within the IRS LB&I division. The request must include, among other things:

(a) a statement of the relevant facts, including a description of the taxpayer's business, the intercompany transactions at issue, and the relationship between the parties;

(b) a detailed description of the IRS's proposed adjustment and its basis;

(c) an identification of the applicable treaty provision(s), including the specific articles under which relief is sought (in this case, Articles 9 and 25);

(d) a description of the double taxation that has resulted or will result from the adjustment;

(e) copies of all relevant documents, including the NOPA, the 30-Day Letter, the taxpayer's Protest, and any closing agreements;

(f) the taxpayer's proposed resolution of the double taxation;

(g) a properly executed power of attorney (Form 2848) authorizing counsel to act on the taxpayer's behalf before the U.S. Competent Authority; and

(h) any other information that may assist the competent authorities in resolving the case.

Filing Fee. There is no filing fee for a MAP request.

Timing. The MAP request must be filed within the timeframe specified in the applicable treaty — in this case, within three years of the "first notification of the action resulting in taxation not in accordance with the provisions of the Treaty." For IRS-initiated adjustments, the relevant trigger is the date of the NOPA or equivalent document. Here, the NOPA was issued on October 12, 2023, establishing a filing deadline of October 12, 2026.

Interaction with Domestic Proceedings. Rev. Proc. 2015-40 specifically addresses the interaction between MAP requests and domestic proceedings, including IRS Appeals and Tax Court litigation. Sections 7.03 through 7.05 of the revenue procedure provide the following framework:

• A taxpayer may simultaneously pursue domestic remedies (Appeals, Tax Court) and competent authority relief. The two processes are not mutually exclusive.

• APMA and IRS Appeals are required to coordinate to avoid inconsistent outcomes. In practice, the U.S. Competent Authority generally defers substantive action on a MAP request while domestic proceedings are pending, and addresses residual double taxation after the domestic proceedings have concluded.

• A taxpayer may file a "protective" or preliminary MAP request to preserve its rights while domestic proceedings are pending. A protective filing need not contain the full substantive documentation required for a complete MAP request; it need only identify the treaty, the tax years, and the nature of the adjustment, and state that the taxpayer intends to supplement the request upon resolution of domestic proceedings.

No Guarantee of Outcome. It is important to note that the U.S. Competent Authority (APMA) does not guarantee any particular outcome in a MAP proceeding. APMA will endeavor to negotiate a bilateral resolution with the Irish Competent Authority, but the competent authorities are not bound to reach agreement, and the taxpayer is not a party to the bilateral negotiations (though the taxpayer may be consulted).

D. OECD Transfer Pricing Guidelines — MAP Provisions

Both the United States and Ireland are members of the Organisation for Economic Co-operation and Development ("OECD") and adhere to the OECD Transfer Pricing Guidelines for Multinational Enterprises and Tax Administrations (the "OECD Guidelines"). Chapter IV of the OECD Guidelines addresses administrative approaches to avoiding and resolving transfer pricing disputes, including the mutual agreement procedure, corresponding adjustments, and advance pricing arrangements.

The OECD Guidelines recognize that MAP is the principal treaty-based mechanism for resolving double taxation arising from transfer pricing adjustments by one Contracting State. The Guidelines emphasize that competent authorities should approach MAP cases with a genuine intention to resolve the double taxation and should give due consideration to the taxpayer's position.

Both the U.S. and Ireland have committed to the OECD/G20 Base Erosion and Profit Shifting ("BEPS") Action 14 minimum standard on MAP, which includes commitments to:

• resolve MAP cases in a timely manner (the OECD target is resolution within 24 months of the MAP filing);

• ensure that MAP access is available in all cases where double taxation arises or may arise;

• implement MAP agreements without delay; and

• provide transparent MAP statistics through the OECD's MAP Statistics framework.

Ireland's track record in MAP proceedings is generally strong. Ireland has been a constructive and cooperative partner in bilateral MAP negotiations, particularly with the United States. The Irish Revenue Commissioners have generally accepted correlative adjustments under treaty MAP provisions in transfer pricing cases, subject to their independent assessment that the primary adjustment is consistent with the arm's-length principle as reflected in the OECD Guidelines. Ireland's peer review under BEPS Action 14 confirmed that Ireland's MAP program is functioning effectively and meets the minimum standard.

Our Irish counsel, Ciarán Thornbury of Thornbury & Keogh, has confirmed informally that, based on his experience with the Irish Revenue Commissioners, Irish Revenue would likely engage constructively in a MAP proceeding involving PPC and PBI, particularly given the materiality of the adjustment and the longstanding bilateral relationship between the U.S. and Irish tax authorities.

IV. Analysis of Whether to Pursue a MAP Request

A. Arguments in Favor of Filing a MAP Request

Several considerations weigh in favor of PPC pursuing a MAP request under Article 25 of the Treaty:

1. Elimination of Double Taxation. The primary and most compelling reason to file a MAP request is the elimination of economic double taxation. Without a corresponding Irish adjustment to reduce PBI's Irish taxable income, PPC and PBI collectively bear the full burden of taxation by both jurisdictions on the same income. At the full proposed adjustment level of $380.4 million, the aggregate double-tax cost is substantial — potentially exceeding $100 million in combined U.S. and Irish taxes on the disputed income. Even at a reduced settlement level, the double tax remains a real and quantifiable cost that can only be eliminated through bilateral action or a unilateral Irish corresponding adjustment. The MAP process is the Treaty-based mechanism specifically designed to achieve this result.

2. Treaty Right. PPC has a clear and well-established right under Article 25(1) of the Treaty to request competent authority assistance. This right is independent of PPC's domestic remedies (Appeals, Tax Court) and exists precisely for situations like the one at hand, where one Contracting State proposes a transfer pricing adjustment that creates double taxation. Failure to exercise this right would leave PPC without recourse to the Treaty's double-tax relief provisions and would require PPC to rely entirely on other, less certain mechanisms (such as foreign tax credits or voluntary action by the Irish Revenue Commissioners).

3. Ireland's General Willingness to Engage. As noted in Section III.D above, Ireland has a strong track record of engaging constructively in MAP proceedings and providing correlative adjustments, particularly in the bilateral U.S.-Ireland context. The Irish Revenue Commissioners have demonstrated a commitment to the arm's-length principle and to the resolution of double taxation through the MAP process. Ciarán Thornbury of T&K has confirmed informally that, based on his experience, Irish Revenue would likely engage constructively. This increases the probability that a MAP request would yield a favorable outcome — i.e., a full or partial correlative adjustment by Ireland.

4. Preservation of Position. Filing at least a protective MAP request ensures that PPC does not inadvertently lose its right to competent authority relief through the passage of time. Although the three-year deadline (October 12, 2026) is not immediately pressing, prudent practice counsels in favor of an early protective filing, particularly given the complexity of the underlying issues and the possibility that domestic proceedings could extend over several years. A protective filing is a low-cost measure that preserves PPC's full range of options.

5. BEPS Action 14 Commitment. Both the United States and Ireland have made public commitments under the BEPS Action 14 minimum standard to ensure effective and timely MAP resolution. OECD MAP statistics for the U.S.-Ireland bilateral relationship show high resolution rates and generally favorable outcomes for taxpayers in transfer pricing MAP cases. These commitments provide a favorable institutional backdrop for PPC's MAP request.

B. Arguments for Deferring the MAP Request

Notwithstanding the foregoing considerations, there are compelling reasons to defer the substantive MAP filing until the outcome of the IRS Appeals process is known:

1. The Adjustment Amount Is Not Yet Final. The IRS has proposed a $380.4 million adjustment, but this amount is subject to review and potential reduction through the Appeals process. As discussed in our separate Appeals strategy memorandum, we believe there is a reasonable basis to achieve settlement at approximately 10–15% of the proposed adjustment — i.e., in the range of $38 million to $57 million. Filing a MAP request on the full $380.4 million proposed adjustment would be premature, as it would request bilateral relief on an amount that has not been finalized and is likely to be materially reduced. A MAP request on a $47.6 million settlement is a fundamentally different undertaking — in scope, complexity, and economic justification — than one on $380.4 million. Deferring the substantive filing allows PPC to right-size the MAP request to the actual adjustment amount.

2. Cost Efficiency. MAP proceedings involve substantial professional fees on both sides of the Atlantic. As discussed in Section VIII below, we estimate total MAP costs in the range of $260,000 to $470,000, encompassing both U.S. counsel fees (C&H) and Irish counsel fees (T&K). If the Appeals process achieves a favorable settlement at a fraction of the proposed adjustment, the double-tax exposure on the settled amount may be sufficiently small that the cost of a formal bilateral MAP proceeding is not economically justified. At a settlement of $47.6 million (midpoint of our target range), the incremental Irish tax at risk is approximately $3.0 million to $6.0 million. While the net benefit of a MAP proceeding would still be positive (approximately $2.5 million to $5.5 million after professional fees), the marginal benefit must be weighed against the time, management attention, and opportunity cost involved. Moreover, if PBI can obtain a unilateral corresponding adjustment from Irish Revenue without a formal MAP filing (as T&K believes may be possible), the cost savings would be significant.

3. Strategic Considerations for Appeals. Filing a MAP request concurrently with or prior to the Appeals process could send an unintended signal to the IRS Appeals Officer that PPC expects a significant adjustment to be sustained and is already preparing for the double-tax consequences. This could undercut PPC's negotiating leverage at Appeals, where PPC's posture should be one of confidence in the strength of its transfer pricing position. An Appeals Officer who perceives that the taxpayer is already "planning for" double taxation may infer that the taxpayer's own assessment of the merits is less favorable than its stated position suggests. While this is a nuanced strategic judgment, we believe the better approach is to maintain a clean negotiating posture at Appeals and defer the MAP filing until after settlement.

4. Timeline Considerations. MAP proceedings typically take 24 to 36 months from filing to resolution, with the OECD target being 24 months. The IRS Appeals process, by contrast, is expected to proceed on a faster timeline: the Appeals conference is scheduled for February 28, 2024, and we anticipate that settlement discussions could conclude within several months thereafter. By deferring the MAP filing until after Appeals, PPC can avoid the burden and complexity of managing simultaneous domestic and bilateral proceedings, and can submit a more focused and efficient MAP request based on the final adjustment amount.

5. Coordination Complexity. Simultaneous pursuit of domestic remedies (Appeals) and competent authority relief (MAP) requires careful coordination under Rev. Proc. 2015-40, §§ 7.03–7.05. While the revenue procedure permits concurrent proceedings, the practical reality is that APMA will generally defer substantive action on a MAP request until domestic proceedings have concluded. Filing a MAP request now would therefore not accelerate the bilateral process; it would simply add an additional layer of administrative coordination and communication obligations for PPC and its advisors.

C. Recommended Approach: Preserve Rights, Defer Filing

Balancing the considerations set forth above, we recommend the following four-step approach:

Step 1 — Protective Filing. PPC should file a brief protective (preliminary) MAP request with the U.S. Competent Authority (APMA) by mid-January 2024. The protective filing should identify the Treaty, the tax years at issue (2017 through 2020), the nature of the proposed adjustment (IRC § 482 transfer pricing adjustment), and the potential for double taxation. The filing should state that PPC is currently pursuing domestic remedies through IRS Appeals and will supplement the MAP request with full supporting documentation upon resolution of the domestic proceedings. This protective filing preserves PPC's rights within the three-year filing window (which runs until October 12, 2026) and ensures that PPC's MAP option remains fully available regardless of the timeline of domestic proceedings.

Although the October 12, 2026, deadline affords ample time, a protective filing now is prudent for several reasons: it establishes PPC's intent on the record with APMA; it facilitates coordination between APMA and Appeals (as required by Rev. Proc. 2015-40); and it eliminates any risk that unforeseen procedural developments could create timing issues.

Step 2 — Coordinate with T&K (Ciarán Thornbury). PPC should instruct T&K to provide informal notification to the Irish Revenue Commissioners that a U.S. transfer pricing adjustment is pending with respect to PBI, that PBI may request a corresponding adjustment under Article 9(2) of the Treaty, and that PPC may file a MAP request under Article 25. This notification serves to preserve PBI's position under Irish law and practice, ensures that the Irish Revenue Commissioners are not surprised by a future MAP or corresponding adjustment request, and opens a constructive channel of communication. Leila Nazari is currently coordinating with T&K on the timing and substance of this notification, and we expect to send formal instructions to T&K once the Appeals conference date of February 28, 2024, is confirmed.

Step 3 — Await Appeals Outcome. PPC should proceed with the IRS Appeals process on the timeline currently contemplated, with the Appeals conference scheduled for February 28, 2024. Our separate memorandum on Appeals strategy sets forth PPC's substantive positions in detail. If the Appeals process achieves a favorable settlement in our target range (10–15% of $380.4 million, i.e., approximately $38 million to $57 million), the double-tax exposure will be known with precision, and PPC can make an informed decision regarding the next steps for Irish-side relief.

Step 4 — Post-Settlement Evaluation. Upon conclusion of the Appeals process and execution of a Form 870-AD (or Form 906 Closing Agreement, if appropriate), PPC should conduct a comprehensive evaluation of the following questions:

(a) What is the settled adjustment amount and its tax impact? At our target settlement midpoint of $47.6 million, the incremental U.S. federal income tax would be approximately $10.0 million, and the Irish tax already paid by PBI on the corresponding income would be approximately $3.0 million to $6.0 million.

(b) Can PBI obtain a unilateral corresponding adjustment from the Irish Revenue Commissioners without invoking the formal MAP process? This is the preferred outcome, as it would be significantly faster and less costly than a bilateral MAP proceeding. T&K's preliminary assessment is that Irish Revenue has granted such unilateral adjustments in prior cases, particularly where the U.S. adjustment is supported by a closing agreement or other formal resolution document.

(c) If a unilateral adjustment is not available, is a formal bilateral MAP request necessary to compel Ireland to provide correlative relief? This would be the appropriate course if Irish Revenue is unwilling to act unilaterally or if the adjustment amount is large enough to warrant the formal process.

(d) Does the cost-benefit analysis justify a formal MAP proceeding? We estimate total MAP costs in the range of $260,000 to $470,000, with a timeline of 24 to 36 months. This must be weighed against the expected benefit (Irish tax relief of approximately $3.0 million to $6.0 million at the settlement midpoint) and the alternative of seeking a less costly unilateral corresponding adjustment.

V. Procedural Requirements for a MAP Request

A. U.S. Filing Requirements (Rev. Proc. 2015-40)

Should PPC elect to file a substantive MAP request with the U.S. Competent Authority, the filing must comply with the requirements of Rev. Proc. 2015-40. The following is a summary of the key procedural requirements:

Submission Address. The MAP request must be submitted to the U.S. Competent Authority, currently within the Advance Pricing and Mutual Agreement Program (APMA), IRS LB&I. The request should be addressed to the Director, APMA, and may be submitted electronically or by mail in accordance with the procedures specified in Rev. Proc. 2015-40.

Required Contents. The MAP request must include all of the items described in Section III.C above, including a comprehensive statement of facts, a description of the IRS adjustment, identification of the applicable treaty provisions, a description of the resulting or anticipated double taxation, copies of all relevant IRS documents (NOPA, 30-Day Letter, Protest, closing agreement), the taxpayer's proposed resolution, and a properly executed Form 2848 power of attorney.

Filing Fee. There is no filing fee associated with a MAP request.

Timing. As noted above, the MAP request must be filed within three years of the first notification of the action resulting in taxation not in accordance with the Treaty. The NOPA was issued on October 12, 2023, establishing a filing deadline of October 12, 2026.

Coordination with Appeals. Rev. Proc. 2015-40, §§ 7.03–7.05, provides detailed guidance on the coordination of MAP requests with pending domestic proceedings. The key principles are:

(a) A MAP request may be filed while IRS Appeals proceedings are pending. The filing of a MAP request does not suspend or alter the Appeals process.

(b) APMA and IRS Appeals are required to coordinate to avoid inconsistent outcomes. In practice, this means that APMA will generally defer substantive engagement with the foreign competent authority until the domestic proceedings have concluded, unless the taxpayer specifically requests otherwise or the circumstances warrant earlier bilateral engagement.

(c) Upon conclusion of domestic proceedings, the taxpayer should supplement the protective MAP filing with complete documentation, including the settlement terms and a computation of the residual double taxation.

(d) The U.S. Competent Authority retains the authority to negotiate a bilateral resolution with the Irish Competent Authority that may differ from the domestic settlement terms, but in practice, APMA generally seeks to build upon the domestic resolution rather than reopen settled issues.

B. Irish Filing Requirements

On the Irish side, PBI (or PPC on PBI's behalf) may file a request with the Irish Revenue Commissioners for a corresponding adjustment under Article 9(2) of the Treaty. The Irish MAP filing requirements are as follows:

Governing Framework. Ireland's MAP procedures are governed by Irish Revenue guidance on treaty mutual agreement procedures, which generally align with the OECD MAP framework and the BEPS Action 14 minimum standard. Ireland has published guidance on MAP requests, including the information required, the process for engagement with the foreign competent authority, and the timeline for resolution.

Required Contents. The Irish MAP request should include a description of the relevant facts, the U.S. adjustment and its basis, the applicable treaty provisions, a computation of the double taxation, and copies of relevant U.S. documents (including the NOPA or closing agreement).

Counsel. T&K (Ciarán Thornbury) will handle the preparation and filing of the Irish-side MAP request or corresponding adjustment application, in coordination with C&H.

Timing. Irish Revenue generally processes MAP requests within the OECD target timeline of 24 months, although complex transfer pricing cases may take longer. The timeline begins upon receipt of a complete MAP request by the Irish Competent Authority.

C. PHL (Luxembourg) Considerations

As noted in Section II.A.2 above, PHL is treated as a disregarded entity for U.S. federal income tax purposes. For purposes of the Treaty MAP analysis, the relevant bilateral relationship is between the United States and Ireland — specifically, between PPC (U.S. resident) and PBI (Irish resident). Luxembourg is not a party to the MAP in this context.

We have considered whether PHL's status as a Luxembourg société à responsabilité limitée could create a separate treaty claim or otherwise complicate the MAP analysis. We do not believe it does, for the following reasons:

(a) PHL is disregarded for U.S. federal tax purposes. For purposes of the IRC § 482 adjustment and the Treaty MAP request, PPC — not PHL — is the U.S. party to the intercompany transactions at issue.

(b) The intercompany transactions giving rise to the IRS's proposed adjustments (CSA cost-sharing payments, Legacy License royalties) are between PPC and PBI, not between PHL and PBI. PHL is not a party to either the CSA or the Legacy License.

(c) The U.S.-Luxembourg income tax treaty is not implicated because no adjustment to PHL's income is proposed or contemplated, and PHL does not have Luxembourg taxable income at risk.

We recommend confirming this analysis with T&K to ensure that there are no Irish-side complications arising from PHL's position in the ownership chain, but we do not anticipate any issues.

VI. Potential Outcomes of a MAP Request

A. Full Correlative Adjustment by Ireland

The best-case outcome of a MAP request would be a full correlative adjustment by the Irish Revenue Commissioners — i.e., Ireland would agree that the U.S. § 482 adjustment (or the settled portion thereof) is consistent with the arm's-length principle and would make a corresponding downward adjustment to PBI's Irish taxable income for the relevant years (2017–2020). PBI would receive a refund of, or credit for, the Irish corporation tax overpaid on the income now reallocated to PPC. Double taxation would be fully eliminated.

We assess the likelihood of this outcome as moderate to high, particularly if the U.S. adjustment is settled through the Appeals process and memorialized in a closing agreement. Irish Revenue is generally receptive to correlative adjustments when the U.S. adjustment is supported by a credible arm's-length analysis and is not perceived as a unilateral revenue-maximizing measure by the IRS. The existence of a closing agreement provides Irish Revenue with a firm basis for determining the amount of the correlative adjustment. T&K has confirmed that, in their experience, Irish Revenue has provided full correlative adjustments in analogous cases involving U.S. § 482 adjustments to Irish subsidiaries of U.S. multinational groups.

However, the outcome is not guaranteed. Irish Revenue retains the right to independently evaluate the U.S. adjustment under the arm's-length principle and may disagree with elements of the IRS's methodology or the settlement terms. This risk is somewhat mitigated by the fact that the MAP process is bilateral — the competent authorities negotiate with each other, and the U.S. Competent Authority has an institutional interest in securing correlative adjustments from treaty partners to maintain the credibility and effectiveness of the U.S. MAP program.

B. Partial Correlative Adjustment

A possible intermediate outcome is that Irish Revenue agrees to only a partial correlative adjustment, reflecting its disagreement with certain elements of the U.S. adjustment or its independent assessment that only a portion of the reallocation is justified under the arm's-length principle. This would partially relieve double taxation but leave PPC/PBI with some residual double-tax burden.

For example, Irish Revenue might agree to a correlative adjustment with respect to the CSA cost-sharing ratio (where the IRS's case may be stronger) but disagree with the royalty rate increase (where the IRS's comparability analysis may be more vulnerable to challenge). In such a scenario, double taxation would be eliminated on the portion of the adjustment that Ireland accepts but would persist on the portion that Ireland rejects.

C. No Agreement / Failure of MAP

In the least favorable scenario, the competent authorities are unable to reach agreement, and no correlative adjustment is provided. Double taxation on the full adjustment (or settled amount) would persist, and PPC/PBI would bear the aggregate U.S. and Irish tax burden.

This outcome is a real possibility, particularly given a significant limitation of the current U.S.-Ireland Treaty: the absence of a mandatory binding arbitration clause. Unlike certain other U.S. tax treaties (e.g., the U.S.-Germany treaty, the U.S.-Canada treaty, and the U.S.-Belgium treaty, each of which contains an arbitration provision that can be invoked if the competent authorities fail to reach agreement within a specified period), the U.S.-Ireland Treaty does not include a binding arbitration mechanism. This means that if the U.S. and Irish competent authorities are unable to agree on a resolution, there is no mechanism to compel a binding outcome. The taxpayer would bear the residual double tax with no further recourse under the Treaty.

We note that Ireland has entered into arbitration provisions in certain of its other bilateral tax treaties, and there have been periodic discussions regarding the possibility of amending the U.S.-Ireland Treaty to include such a provision. However, no such amendment has been adopted, and there is no immediate prospect of one.

The practical significance of this limitation should not be overstated, however. Based on OECD MAP statistics and T&K's experience, the resolution rate for U.S.-Ireland MAP cases is high, and outright failures are relatively uncommon. The absence of an arbitration backstop is more of a theoretical risk than a practical one, but it is a risk that PPC should be aware of in evaluating the MAP option.

D. Unilateral Corresponding Adjustment (Outside MAP)

An alternative to the formal bilateral MAP process is for PBI to request a unilateral corresponding adjustment directly from the Irish Revenue Commissioners, outside the MAP framework. Under this approach, PBI would apply to Irish Revenue under Article 9(2) of the Treaty (and/or under Irish domestic law) for a reduction of its Irish taxable income corresponding to the U.S. § 482 adjustment, without invoking the formal competent authority consultation process.

This approach has several advantages:

• Speed: A unilateral corresponding adjustment can be obtained significantly faster than a bilateral MAP proceeding, as it does not require bilateral negotiation between the two competent authorities.

• Cost: The cost of a unilateral request is significantly lower, as it involves only Irish counsel (T&K) and does not require the full preparation of a U.S. MAP filing or coordination with APMA.

• Simplicity: The administrative burden is lighter, and the process can be managed by T&K in direct engagement with Irish Revenue without the complexity of bilateral coordination.

T&K has advised that Irish Revenue has granted unilateral corresponding adjustments in prior cases, particularly where the U.S. adjustment is supported by a formal closing agreement (Form 906) and the adjustment amount is clearly quantified. However, the availability of a unilateral adjustment is at the discretion of Irish Revenue, and there is no guarantee that it will be granted. If Irish Revenue declines to provide a unilateral adjustment, PPC would need to fall back on the formal MAP process.

We recommend pursuing the unilateral approach as the first option following the Appeals settlement, with the formal MAP as a fallback. This sequence minimizes cost and maximizes efficiency.

VII. Interaction with Other Tax Provisions

A. GILTI and BEAT (TY 2018–2020)

The IRC § 482 adjustment and any resulting MAP or corresponding adjustment would have secondary effects on PPC's computations under the Global Intangible Low-Taxed Income ("GILTI") provisions of IRC § 951A and the Base Erosion and Anti-Abuse Tax ("BEAT") provisions of IRC § 59A, both of which are effective for tax years beginning after December 31, 2017 (i.e., applicable to TY 2018, 2019, and 2020 for PPC).

Specifically, if the § 482 adjustment increases PPC's U.S. taxable income and, through a MAP or corresponding adjustment, decreases PBI's Irish taxable income, the net effect on PPC's GILTI inclusion is as follows: PBI's tested income for GILTI purposes would be reduced by the amount of the corresponding adjustment, which would reduce PPC's GILTI inclusion under § 951A. This reduction in GILTI inclusion would partially offset the increase in PPC's U.S. taxable income from the § 482 adjustment itself. The magnitude of this offset depends on PPC's overall GILTI computation, including the net deemed tangible income return under § 951A(b)(2), PPC's foreign tax credit position under § 960(d), and other factors.

Similarly, the § 482 adjustment could affect PPC's BEAT computation. If the intercompany payments from PBI to PPC (cost-sharing payments, royalties) constitute "base erosion payments" under § 59A(d), an increase in those payments (reflecting the § 482 adjustment) would increase PPC's "base erosion tax benefits" and could affect the BEAT liability calculation. Conversely, if a corresponding adjustment reduces the intercompany payments, the BEAT impact would be mitigated.

This interplay is complex and should be carefully modeled before finalizing any MAP request or corresponding adjustment application. We have flagged this issue for Garrett Simmons, who is preparing a separate analysis of the GILTI and BEAT impact of the proposed adjustments and potential settlement scenarios. A cross-reference to that analysis will be incorporated into the MAP filing, if one is ultimately prepared.

B. Foreign Tax Credits

If Ireland does not provide a corresponding adjustment — either through the MAP or unilaterally — PPC may be entitled to claim additional foreign tax credits under IRC § 901 or § 960 for the Irish taxes paid by PBI on the income now reallocated to PPC by the § 482 adjustment. This would provide partial, though imperfect, relief from the double taxation, as the foreign tax credit would reduce PPC's U.S. tax liability on the doubly-taxed income.

However, the foreign tax credit analysis is complex and depends on several factors, including:

(a) PPC's overall foreign tax credit position for each year at issue, including whether PPC is in an excess credit or excess limitation position in the relevant foreign tax credit limitation basket (general category income);

(b) the character and source of the income at issue, which affects the foreign tax credit limitation under IRC § 904;

(c) the creditability of the Irish taxes under IRC § 901 and the applicable Treasury Regulations, including the requirements that the Irish tax be an income tax (or a tax in lieu thereof) within the meaning of Treas. Reg. § 1.901-2;

(d) the application of the GILTI foreign tax credit provisions under IRC § 960(d), which impose an 80% haircut on deemed-paid credits for GILTI inclusions; and

(e) the overall limitation computation, including the interaction with PPC's other foreign-source income and foreign taxes from non-Irish jurisdictions.

In short, while foreign tax credits provide a potential alternative mechanism for mitigating double taxation, they are an imperfect substitute for a corresponding adjustment, and their availability and amount cannot be determined without a detailed computation that takes into account PPC's full credit profile. We note this as an alternative but do not recommend relying on it as the primary relief mechanism.

C. Knowledge Development box (KDB) Impact